nSTRIDE® APS

nSTRIDE® APS at Mount Stuart Hospital

nSTRIDE® APS is a new and proven treatment that processes your own blood sample and injects it back into your knee joint to alleviate osteoarthritis pain.

nSTRIDE® Autologous Protein Solution (APS) is an autologous treatment for osteoporosis, which means it is ‘from your own body’.

In an osteoarthritic knee, inflammatory “bad” proteins outnumber anti-inflammatory “good” proteins. This imbalance results in knee pain and cartilage degeneration.

nSTRIDE® APS brings balance back to your knee by injecting concentrated high levels of “good” proteins into your inflamed knee joint. These “good” proteins are produced from your own blood. They block the “bad” proteins responsible for your inflammatory joint condition. This decreases pain and slows cartilage degeneration. Other “good” proteins then improve your cartilage health.

What are the benefits of nSTRIDE® APS?

The benefits of nSTRIDE® APS are:

• decreases or eliminates pain in your knee joint 
• helps to restore mobility, flexibility, and comfort
• less stiffness
• slower cartilage degeneration
• may slow the progression of osteoarthritis 
• a single injection in your doctor’s office

The benefits of nSTRIDE® APS should last for 24 to 36 months.

When to think about having nSTRIDE® APS treatment?

If you suffer from knee joint pain and stiffness due to mild to moderate osteoarthritis and you are looking for a natural and effective treatment, you might think about having nSTRIDE® APS treatment. 

Is nSTRIDE® APS right for me?

nSTRIDE® APS may be right for you if:

  • you have mild to moderate knee osteoarthritis
  • you are looking for a treatment that can help your knee pain and limited mobility
  • your knee osteoarthritis reduces your ability to work and diminishes your self-esteem
  • you like the idea of an autologous treatment, meaning ‘from your own body’
  • you prefer a more natural treatment rather than using steroid injections or steroid injections haven’t worked for you
  • you are happy to engage in a comprehensive rehabilitation and training program for knee osteoarthritis together with nSTRIDE® APS treatment to optimise your pain reduction
  • you would like a one-off procedure that will relieve knee osteoarthritis symptoms for up to three years
  • you want to get back to doing the things you love.

What can you expect during nSTRIDE® APS treatment?

Your nSTRIDE® APS treatment will be performed in your orthopaedic knee surgeon’s office and takes 20 to 30 minutes. 

A small amount of blood is drawn from a vein in your arm and processed to concentrate white blood cells, platelets, and plasma proteins into a small volume of anti-inflammatory “good” protein solution. This is injected into your affected knee joint area.

What does recovery from nSTRIDE® APS look like?

nSTRIDE® APS is an outpatient treatment and so you can expect a quick recovery.

After your injection, you may experience some side effects. These can include swelling in your joint, bruising, and local pain associated with drawing your blood draw or your knee injection.

Over the first four to five days, you may experience pain in your injection site or your knee, or both. Do not take nonsteroidal anti-inflammatory drugs (NSAIDs) to manage your pain but you can take other analgesics such as paracetamol.

For the first 14 days, you should keep your activity level to a minimum and not exceed your pre-injection activity levels. 

As a minimum, you should limit activities including walking for the first four to five days to prevent inflammation and swelling of your joint. Training and sports should be avoided for at least four to five days after treatment and ideally for 14 days. This is particularly important if you normally participate in high-intensity or long-distance sports or training.

After four to five days, you can expect a small reduction in swelling, stiffness, and pain. You may experience pain relief after one to two weeks. But most patients, feel pain relief between four and eight weeks after treatment.

A significant reduction in pain may take up to eight weeks and can occur suddenly or gradually.

How long can I expect the benefits from nSTRIDE® APS to last?

You can expect the benefits from nSTRIDE® APS to last 24 to 36 months.

Mount Stuart Hospital Specialists

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